My apologies to those who looked for blog updates in the past few weeks and didn't find them. I was traveling in places with poor Internet connectivity, and was unable to keep up with my correspondence.
Last week's Grand Rounds was canceled due to QRM from the ARRL Sweepstakes, so, according to Warren KD4GUA, the topic was shifted to this week's net:
This Sunday, by request and as a follow-up from the lead story in the
Dec. Aether, we will attempt to tackle the P450 system in the liver (and
other places). The subject is complex and scary as we begin to get an
insight into why drugs have side effects. Their power is determined by
this system which is NOT THE SAME IN EVERY HUMAN, thus, we were not all
born alike. What is causing the high development costs of drugs is that
one 325 mg Aspirin, or any other drug, does not have the same effect,
for example, in everyone.
We are entering the stage of
PERSONALIZED MEDICINE whereas to get the max benefits it has to be the
right dose of the right drug that is not induced or inhibited by the
P450 system which breaks down 70% of all drugs and is not induced or
inhibited by other drugs. A giant problem that is simmering below the
headlines which the legal eagles are waiting with open fangs to exploit.
Have a martini and enjoy the show!
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